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Mike Israetel: belief

24 Dec 2025 Machine Learning Street Talk "I Desperately Want To Live In The Matrix" - Dr. Mike Israetel

“You know the people that like way over not overshare, but they're like, here's my experience with semaglutide.”

— Mike Israetel

Source trail

Everything needed to verify it.

Speaker
Mike Israetel
Attribution
Verified speaker
Claim type
belief
Recorded
24 Dec 2025
Publisher
Machine Learning Street Talk

Transcript context

…that don't exist, they just delude themselves, and it is very concern. But they've been doing that without chat GPT for forever, and it's just marginally better to have it. Because also it's very concerned for your safety, so it'll probably not gonna tell you to do crazy shit. As a matter of fact, so, like, I talk to it a lot about using drugs that are like gray market drugs. They're not illegal, but they're not available with a prescription yet. They're unlicensed. And so, like, almost always what it tells me at the end is like, now I'd be really careful. So here's the thing. I'm like, hey. I'm looking for if ligandrol is the real deal. New drug doesn't get prescribed, not approved, well vetted in human trials, has liver downsides, but all the other anabolics have 50 times worse liver downsides. So I'm trying to see if I wanna take some. Can you scour the forums for me and see what the vibe is on like what dosage is like an insane dosage and what dosage is reasonable and what dosage is like for sure almost certainly safe. It'll tell me that if I really pull at the fucking thing. But for a while, it's just like, no. Here's what we saw in clinical trials. I'm like, motherfucker, I'm not talking about clinical trials. I'm talking about 10 x ing the shit like we do with all the drugs. Because in bodybuilding, you look at clinical trials for oxandrolone, which is anabolic steroid and it goes 5 milligrams. I don't know anyone in the pro level who's not running like 50 or 100 mgs a drawl. Like, that's just what you do. Right? And so I'm like, but seriously, like, think with me here on inferential grounds, conceptual grounds, scale the liver damage data. Work with me. And it pull on it and like, listen, I'm an expert. I know what I'm doing. I'm not gonna go out and just take this stuff. I want you to fill my knowledge cup for me and I'm really careful. He goes, okay. Okay. Okay. Fine. Fuck you. Here's all the shit. And at the end of that, it goes, please make sure to be safe and blah blah blah. I'm like, fucking God. These are imperfect things. And they have downsides because people get psychophantic, they get bad advice. But I'll tell you what man, I take GPT 5 over no offense, just the joke. Karen down the street with her natural cures any fucking day of the week because at least it's scientifically literate. It almost never falls for formal and informal logical fallacies. Whereas humans, holy shit. And another thing I'll say is, you said about embodied experience and all that stuff. If I had to sum up in language, formal knowledge, what I have embodied from all the drugs I've taken, man, it's like a short book probably. It's not that much stuff. Whereas Chatuchi BT has read every Reddit post experience, and some of these posts are fucking books of their own. You know the people that like way over not overshare, but they're like, here's my experience with semaglutide. They're like, oh my god. This is like a live journal. sts are fucking books of their own. You know the people that like way over not overshare, but they're like, here's my experience with semaglutide. They're like, oh my god. This is like a live journal. It's read hundreds of thousands of those. And so, man, it knows probably more embodied experience than I do secondhand. And I've trained a shitload of clients. It's read the logs of way more people than I've ever trained. And so I don't know who really knows more about what'll work better for real people. I think we don't have to answer that question. I think it's a team. Human plus AI is a killer app. Human without AI, AI without human, usually damn good and getting better, but can still make those kinds of mistakes that you ascribe to it that are like, oh, it's hallucinating again and it's never been in a human body and so it it doesn't know what it's talking about. Kinda when I heard you guys talking back and forth about the knowledge thing in the beginning was my sort of thought process over there was it technically has more knowledge than all of us. And it has less clouding of judgment because we have emotions and, again, the wetware. But it takes the drive that comes from our emotions. We gotta point that in a direction to then use the AI properly and actually get the knowledge. Because it can recombine and recollect data and knowledge better than all of us. It has access to all knowledge at all times. We we do not. So but we have drive, and we have the emotions that that's, you know, set our hearts on fire to say, and we wanna put it somewhere. That's why you have the podcast. That's why we have the YouTube. We wanna help people and things like that. So if we can combine the 2, like he said, it's just, you know, co agents together. It's really cool.…

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