High Signal Podcasts Evidence ledger
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Daniel Carpenter

Published podcast speaker

Claims
24
Episodes
1
Shows
1
Named items
0

Claim ledger

What Daniel said.

13 transcript-backed records

01 / belief

I’m not saying I agree with all of these folks, but I do think that, right now, all of our attention on notice-and-comment rulemaking — and for that matter, cost-benefit analysis as concomitant to it — misses the fact that there are people who are close observers of this space — and now a very empirically sophisticated observer in this space, Brian Libgober — who believe that most of the action is actually occurring before notice and comment starts.

“I’m not saying I agree with all of these folks, but I do think that, right now, all of our attention on notice-and-comment rulemaking — and for that matter, cost-benefit analysis as concomitant to it — misses the fact that there are people who are close observers of this space — and now a very empirically sophisticated observer in this space, Brian Libgober — who believe that most of the action is actually occurring before notice and comment starts.”
Publisher
Conversations with Tyler

02 / belief

Whether it’s made folks better off or worse off — that’s much harder to tell, but I would argue, in fact, that if you proactively embed voices — interests that wouldn’t otherwise be represented — that you’ll actually open up the conversation.

“Whether it’s made folks better off or worse off — that’s much harder to tell, but I would argue, in fact, that if you proactively embed voices — interests that wouldn’t otherwise be represented — that you’ll actually open up the conversation.”
Publisher
Conversations with Tyler

03 / belief

Then there’s no incentive, or very weak incentives, for anybody to do randomized clinical trials, which I would argue is one of the most important scientific revolutions of the 20th century.

“Then there’s no incentive, or very weak incentives, for anybody to do randomized clinical trials, which I would argue is one of the most important scientific revolutions of the 20th century.”
Publisher
Conversations with Tyler

04 / belief

Actually, in some respects, I think we need to know a fair amount about what postal workers do without, say, calling for Amazon tracking. But if we think that postal workers are misplacing ballots or not providing birth control pills or something like that, then we should probably have some way of picking up on that kind of nefarious behavior.

“Actually, in some respects, I think we need to know a fair amount about what postal workers do without, say, calling for Amazon tracking. But if we think that postal workers are misplacing ballots or not providing birth control pills or something like that, then we should probably have some way of picking up on that kind of nefarious behavior.”
Publisher
Conversations with Tyler

05 / belief

I gave a talk recently to a group in Israel and Europe on regulation, where I said the big bullet we dodged in the past year was one in which there was all this pressure, in summer 2020, on the FDA to quicken a whole set of therapies for coronavirus and COVID-19. This obviously started with hydroxychloroquine, which I think the jury is in on that now — not effective; convalescent plasma — probably very effective, but its rollout certainly didn’t help.

“I gave a talk recently to a group in Israel and Europe on regulation, where I said the big bullet we dodged in the past year was one in which there was all this pressure, in summer 2020, on the FDA to quicken a whole set of therapies for coronavirus and COVID-19. This obviously started with hydroxychloroquine, which I think the jury is in on that now — not effective; convalescent plasma — probably very effective, but its rollout certainly didn’t help.”
Publisher
Conversations with Tyler

07 / belief

I would say two things. Number one, it’s a brute mechanism, but the mechanism of what I would call approval regulation, which is, basically, the FDA as a veto player granting access to profitable markets creates very, very powerful incentives for R&D.

“I would say two things. Number one, it’s a brute mechanism, but the mechanism of what I would call approval regulation, which is, basically, the FDA as a veto player granting access to profitable markets creates very, very powerful incentives for R&D.”
Publisher
Conversations with Tyler

08 / belief

What the FDA does in a lot of these cases is allows for a molecule to be approved, say, cisplatin would be an example of the first platinum-based chemotherapy, and then basically knows — I think the FDA knows that when a lot of these molecules are out there, there’s going to be off-label prescribing.

“What the FDA does in a lot of these cases is allows for a molecule to be approved, say, cisplatin would be an example of the first platinum-based chemotherapy, and then basically knows — I think the FDA knows that when a lot of these molecules are out there, there’s going to be off-label prescribing.”
Publisher
Conversations with Tyler

09 / belief

Knowing some people who’ve been involved in the space, and seeing also what’s gone on worldwide, I would say one agency that has been captured or plausibly captured would be the Nuclear Regulatory Commission.

“Knowing some people who’ve been involved in the space, and seeing also what’s gone on worldwide, I would say one agency that has been captured or plausibly captured would be the Nuclear Regulatory Commission.”
Publisher
Conversations with Tyler

12 / belief

Native American women in the United States were petitioning in ways that were more innovative, even compared to white women. But as they saw this — what I call the accountability of voice, the idea that their voices could matter, not only in the arguments they put forth, but also in the weight of the numbers — I think that became a much more powerful motivator for women’s rights movements to make bolder and bolder claims for the vote.

“Native American women in the United States were petitioning in ways that were more innovative, even compared to white women. But as they saw this — what I call the accountability of voice, the idea that their voices could matter, not only in the arguments they put forth, but also in the weight of the numbers — I think that became a much more powerful motivator for women’s rights movements to make bolder and bolder claims for the vote.”
Publisher
Conversations with Tyler
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