Lex Fridman: commitment

Transcript context

…Yeah. I mean, the goal there comes from experience. I mean, we stand on the shoulders of people that made Utah Arrays and used Utah Arrays for decades before we ever even came along. Neuralink arose, partly this approach to technology arose out of a need recognized after Utah Arrays would fail routinely because the rigid electrodes, those spikes that are literally hammered using an air hammer into the brain, those spikes generate a bad immune response that encapsulates the electrode spikes in scar tissue essentially. And so one of the projects that was being worked on in the Anderson Lab at Caltech when I got there was to see if you could use chemotherapy to prevent the formation of scars. Things are pretty bad when you’re jamming a bed of nails into the brain, and then treating that with chemotherapy to try to prevent scar tissue, it’s like, maybe we’ve gotten off track here, guys. Maybe there’s a fundamental redesign necessary. And so Neuralink’s approach of using highly flexible, tiny electrodes avoids a lot of the bleeding, avoids a lot of the immune response that ends up happening when rigid electrodes are pounded into the brain. And so what we see is our electrode longevity and functionality and the health of the brain tissue immediately surrounding the electrode is excellent. I mean, it goes on for years now in our animal models. What do most people not understand about the biology of the brain? We will mention the vasculature. That’s really interesting. I think the most interesting maybe underappreciated fact is that it really does control almost everything. I don’t know, for an out of the blue example, imagine you want a lever on fertility. You want to be able to turn fertility on and off. There are legitimate targets in the brain itself to modulate fertility, say blood pressure. You want to modulate blood pressure, there are legitimate targets in the brain for doing that. Things that aren’t immediately obvious as brain problems are potentially solvable in the brain. And so I think it’s an under-explored area for primary treatments of all the things that bother people.…

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